Delve into the world of submicron particles with ease — this machine has simple analog controls and no electronics, making it easy to operate. The explosion-proof and easily autoclavable M-110Y Microfluidizer^® processor is ideal for pharmaceutical applications and for prototyping nonstandard applications.

How It Works

The M-110Y is flexible enough for all your high-pressure processing needs. With an air-powered intensifier pump, this processor safely and easily maintains steady pressures, accelerating the product stream to extreme velocities, and achieving remarkably tight particle size distributions and unprecedented particle size reductions. Constantly applied, tightly controlled process pressures ensure that every milliliter of your product is subjected to the same shear forces within the ceramic interaction chamber. As a result, you get the most consistent high-pressure homogenization results possible, including uniform particle and droplet size reduction (often submicron), deagglomeration and high-yield cell disruption.

Recommended Uses

• Cell Disruption
• Nanoemulsions
• Nanodispersions
• Submicron Liposomes
• Submicron Encapsulation
• Microcapsules
• Deagglomeration

Unique Benefits

• Operates at a pressure range of 206 – 1586 bar (3,000 – 23,000 psi)
• Handles sample sizes from 60 ml to continuous
• Maximizes energy-per-unit of fluid volume, yielding superior submicron-scale particle size reductions
• Produces a product flow rate of 100 – 600 ml/min
• Offers easy Clean-in-Place capability and simple maintenance

Standard Features

• Unique wear-resistant ceramic or diamond (optional) fixed-geometry interaction chamber
• Guaranteed scaleup to production-scale machines
• All wetted metal parts — 300 series stainless steel, 17-4 PH stainless steel or Nitronic 60
• Chrome-plated plunger
• Open-jacket cooling coil
• Air powered and explosion-proof
• Sanitary fittings
• Product path is immersible in cooling or heating bath
• CE compliant

Optional Features

• 400 ml stainless steel manual pressure feed reservoir
• 2 liter stainless steel reservoir
• 7.6 liter (2 gallon) pressurized feed tank
• 2 liter stainless steel pressurized reservoir
• Tungsten Carbide plunger in pump
• Special designs and construction materials available upon request
• Autoclavable (sterilizable to 121˚C) air motor
• Air tank regulator
• Sanitary pressure transducer with digital readout
• Dual feed assembly
• Diamond interaction chamber
• Product temperature sensors and indicators
• IQ/OQ documentation
• Kalrez/Chemraz O-rings
• Factory acceptance test (FAT)
• Site acceptance test (SAT)
• Startup training